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Dr. Pinto’s Research: Bird’s Eye View

 

Phase 1:

Identifying genetic changes associated with chemotherapy resistance in test tube studies on white blood cells from healthy volunteers.

Phase 2:

Validating the presence of genetic changes associated with chemotherapy resistance in the DNA of chemotherapy resistant patients (i.e., patients who died following chemotherapy) but not others.

Phase 3:

Predicting chemotherapy resistance in cancer patients by testing their DNA for genetic changes associated with chemotherapy resistance prior to chemotherapy.

Phase 4:

Personalizing treatment for cancer patients based on the results of testing of their DNA for genetic changes associated with chemotherapy resistance when first diagnosed with cancer.